"Look AHEAD: No CVD benefit with lifestyle intervention in diabetics"
Heart Jun 24
http://www.theheart.org/article/1555145.do
"In speculating as to why the study failed to show a difference in cardiovascular outcomes, the Look AHEAD investigators note that the differential weight loss between the intervention and control arms averaged 4.0% over the course of the study but just 2.5% at the end. Such a small difference might not have been sufficient to have an effect on cardiovascular events."